INVESTIGATION OF THE N-GLYCOSYLATION OF THE SARS-COV-2 S PROTEIN CONTAINED IN VLPS PRODUCED IN NICOTIANA BENTHAMIANA

Investigation of the N-Glycosylation of the SARS-CoV-2 S Protein Contained in VLPs Produced in Nicotiana benthamiana

The emergence of the SARS-CoV-2 coronavirus pandemic in China in late 2019 led to the fast development of efficient therapeutics.Of the major structural proteins encoded by the SARS-CoV-2 genome, the SPIKE (S) protein has attracted considerable research interest because of the central role it plays in virus entry into host cells.Therefore, to date,

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Contact lens associated keratitis due to Tintelnotia destructans

We report the first case of Tintelnotia destructans associated keratitis in a contact lens Show halter wearer in Australia.Corneal scrape showed fungal elements on direct microscopy leading to a prompt diagnosis of fungal keratitis and early topical and systemic antifungal therapy.The isolate was eventually identified by ITS gene sequencing.This ca

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25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes

A novel innate immune strategy, involving specific cholesterol oxidation products as effectors, has begun to reveal connections BODY WASH between cholesterol metabolism and immune response against viral infections.Indeed, 25-hydroxycholesterol (25HC) and 27-hydroxycholesterol (27HC), physiologically produced by enzymatic oxidation of cholesterol, a

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